What is this?
Uterine cancer, also known as endometrial cancer, is a type of cancer that begins in the uterus, it is the most common cancer of the female reproductive system.
Uterine cancers can be categorized into two types: endometrial cancer, which is common, and uterine sarcoma, which is rare. Endometrial cancer is often curable, while uterine sarcoma tends to be more aggressive and challenging to treat.
Risk
factors for endometrial cancer include:
●
Using estrogen-only
hormone replacement therapy (HRT) after menopause
●
Taking tamoxifen to
prevent or treat breast cancer
●
Obesity
●
Having metabolic
syndrome
●
Having type 2 diabetes
●
Exposure of endometrial
tissue to estrogen produced by the body, which can be caused by:
○
Never giving birth
○
Early onset of
menstruation
○
Late onset of menopause
○
Having polycystic ovary syndrome
(PCOS)
●
A family history of
endometrial cancer in a first-degree relative (mother, sister, or daughter)
●
Certain genetic
conditions, such as Lynch syndrome
●
Having endometrial
hyperplasia
●
Older age is a major
risk factor for most cancers, with the likelihood of developing cancer
increasing as one ages.
Sign and Symptoms:
●
Vaginal
bleeding or discharge not associated with menstruation.
●
Vaginal
bleeding after menopause.
●
Difficulty
or pain during urination.
●
Painful
sexual intercourse.
●
Pelvic
pain.
Diagnosis:
●
Pelvic
examination
●
Transvaginal
ultrasound
●
Endometrial
biopsy
●
Hysteroscopy
●
Imaging
tests such as MRI or CT scans
The prognosis and treatment
options depend on several factors:
●
The stage
of the cancer (whether it is confined to the endometrium, involves the uterine
wall, or has spread to other parts of the body)
●
The
appearance of the cancer cells under a microscope
●
Whether
the cancer cells are responsive to progesterone
Endometrial cancer is often
curable because it is typically diagnosed at an early stage.
Treatment:
There are different types of treatments
available for cervical cancer.
● Surgery
● Radiation
therapy
● Chemotherapy
● Targeted
therapy
● Immunotherapy
Surgery: Most patients undergo surgery to remove as
much of the tumor as possible. Types of surgery include:
●
Hysterectomy:
Removal of the uterus, and sometimes the cervix. Variations include partial,
total, vaginal, total abdominal, and total laparoscopic hysterectomy.
●
Unilateral Salpingo-Oophorectomy: Removal of one ovary and one fallopian tube.
●
Bilateral Salpingo-Oophorectomy: Removal of both ovaries and both fallopian tubes.
●
Omentectomy: Removal
of the omentum, a tissue in the peritoneum containing blood vessels, nerves,
lymph vessels, and lymph nodes.
●
Lymph Node Biopsy: Removal of all or part of a lymph node to check for cancer
cells under a microscope.
Prevention:
●
Modifying
lifestyle or dietary habits.
●
Avoiding
known cancer-causing substances.
●
Taking
medications to treat precancerous conditions or to prevent the onset of cancer.